Stuart R. Gallant, MD, PhD In Danielle Ofri’s recent column in The New York Times “My Patients Used to Be Enthusiastic About the Covid Vaccine. …
Medical
Wound Care and Healing
Stuart R. Gallant, MD, PhD CAVEAT: THIS POST INCLUDES PHOTOGRAPHS OF TISSUE INJURIES AND MAY CAUSE SOME READERS DISCOMFORT. An 81-year-old, retired accountant is on…
Nicotine and Vapes
Stuart R. Gallant, MD, PhD Humans have been smoking tobacco for more than 10,000 years, but e-cigarettes (“vapes”) have only existed for less than two…
What The Washington Post Got Wrong About Doctors
Stuart R. Gallant, MD, PhD The Washington Post just published an article by Andrew Van Dam, “How much money do doctors really make and why…
Dietary Choices to Support Weight Control
Stuart R. Gallant, MD, PhD People reach a peak bone mass and muscle mass in their early 20s. After that, any increase in weight typically…
Steroid Hormone Replacement Therapy (Part 2 of 2)
Stuart R. Gallant, MD, PhD Steroid hormone replacement therapy (HRT) is a topic that has been in the scientific and popular press a lot recently. …
Male (Androgen) and Female (Estrogen) Hormone Pharmacology (Part 1 of 2)
Stuart R. Gallant, MD, PhD Steroid hormones are frequently in the news—sometimes in infamy, as in the case of sports doping, but also in many…
Skin pH, Water Content, and Water Loss
Stuart R. Gallant, MD, PhD Our skin does so much for us. Skin protects us against infection and dehydration. Skin allows us to be in…
Oral Delivery of Protein Drugs
Stuart R. Gallant, MD, PhD Proteins and peptides are commonly delivered subcutaneously and by infusion; however, these approaches have disadvantages. Among the chief problems are:…
Pharmaceutical Product Launch
Stuart R. Gallant, MD, PhD Above is a photo from the 1947 launch of the M.V. St. Essylt at J.L. Thompson and Sons was a…
Anti-TNF Medications
Stuart R. Gallant, MD, PhD I have a weakness for old Hollywood movies. The movie still that appears above this paragraph depicts John Carradine in…
Moderna’s Bivalent Booster
Stuart R. Gallant, MD, PhD Back in April, PharmaTopo posted on lipid nanoparticle formulations for Covid-19 vaccines [1]. Because the Moderna bivalent vaccine recently arrived…
Pharmaceutical Design Focus: Clot Busters (2 of 2)
Stuart R. Gallant, MD, PhD In the first part of this post, we looked at urokinase. In the second part, we will look at tissue…
Pharmaceutical Design Focus: Clot Busters (1 of 2)
Stuart R. Gallant, MD, PhD This November will be the 35th anniversary of the approval of tissue plasminogen activator (tPA, alteplase) a leading treatment for…
Amazon’s Push Into Healthcare
Stuart R. Gallant, MD, PhD I was intrigued by Amazon’s recent purchase of One Medical for $3.9B in cash. Amazon is implementing a strategy to…
Why and Where You Should Still Be Wearing a Mask
Stuart R. Gallant, MD, PhD I am sure many of you are so done with Covid 19 that you could not imagine wearing a mask…
Improving the Patient-Doctor Conversation
Stuart R. Gallant, MD, PhD Eventually, all of us need to talk to a doctor or a nurse, maybe about a headache, flu symptoms, or…